707 research outputs found

    Particle Filter Design Using Importance Sampling for Acoustic Source Localisation and Tracking in Reverberant Environments

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    Sequential Monte Carlo methods have been recently proposed to deal with the problem of acoustic source localisation and tracking using an array of microphones. Previous implementations make use of the basic bootstrap particle filter, whereas a more general approach involves the concept of importance sampling. In this paper, we develop a new particle filter for acoustic source localisation using importance sampling, and compare its tracking ability with that of a bootstrap algorithm proposed previously in the literature. Experimental results obtained with simulated reverberant samples and real audio recordings demonstrate that the new algorithm is more suitable for practical applications due to its reinitialisation capabilities, despite showing a slightly lower average tracking accuracy. A real-time implementation of the algorithm also shows that the proposed particle filter can reliably track a person talking in real reverberant rooms.This paper was performed while Eric A. Lehmann was working with National ICT Australia. National ICT Australia is funded by the Australian Government’s Department of Communications, Information Technology, and the Arts, the Australian Research Council, through Backing Australia’s Ability, and the ICT Centre of Excellence programs

    Flow Regime Transition in Trickle Bed Reactors

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    In industry, trickle bed reactors – fixed beds in which gas and liquid reactants flow concurrently downward through catalyst - are often operated at gas and liquid superficial velocities near the transition boundaries between flow regimes, especially the transition between trickle to pulse flow. Previous studies have characterized flow regime transitions as sharp transitions that occur at single superficial liquid velocities for a fixed superficial gas velocity. In reality, transitions evolve gradually over a range of superficial liquid velocities. Experiments were conducted in a fixed bed with air and water flowing concurrently downward using two different packing media. The transitions were characterized using standard deviations in pressure drop measurements complimented by imaging with a high speed camera. Variable changes in the slope of standard deviation of pressure drop versus superficial liquid velocity confirm the transitions develop gradually

    Calibration of audio-video sensors for multi-modal event indexing

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    This paper addresses the coordinated use of video and audio cues to capture and index surveillance events with multimodal labels. The focus of this paper is the development of a joint-sensor calibration technique that uses audio-visual observations to improve the calibration process. One significant feature of this approach is the ability to continuously check and update the calibration status of the sensor suite, making it resilient to independent drift in the individual sensors. We present scenarios in which this system is used to enhance surveillance

    Rational curves on del Pezzo surfaces in positive characteristic

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    We study the space of rational curves on del Pezzo surfaces in positive characteristic. For most primes p we prove the irreducibility of the moduli space of rational curves of a given nef class, extending results of Testa in characteristic 0. We also investigate the principles of Geometric Manin's Conjecture for weak del Pezzo surfaces. In the course of this investigation, we give examples of weak del Pezzo surfaces defined over F2(t)\mathbb{F}_{2}(t) or F3(t)\mathbb{F}_{3}(t) such that the exceptional sets in Manin's Conjecture are Zariski dense.Comment: minor changes, 43 pages, to appear in Transactions of the American Mathematical Society Series B

    On the asymptotic enumerativity property for Fano manifolds

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    We study the enumerativity of Gromov-Witten invariants where the domain curve is fixed in moduli and required to pass through the maximum possible number of points. We say a Fano manifold satisfies asymptotic enumerativity if such invariants are enumerative whenever the degree of the curve is sufficiently large. Lian and Pandharipande speculate that every Fano manifold satisfies asymptotic enumerativity. We give the first counterexamples, as well as some new examples where asymptotic enumerativity holds. The negative examples include special hypersurfaces of low Fano index and certain projective bundles, and the new positive examples include many Fano threefolds and all smooth hypersurfaces of degree d≤(n+3)/3d \leq (n+3)/3 in Pn\mathbb{P}^n.Comment: comments welcome

    RELATIONSHIP BETWEEN MUSCLE VOLUME AND STRENGTH ASYMMETRY IN ELITE ATHLETES: INVESTIGATION OF THE QUADRICEPS FEMORIS AND HAMSTRING MUSCLES

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    The purpose of this study was to examine the relationship between muscle volume asymmetries and strength asymmetries of the lower extremity. 26 highly trained athletes underwent isometric and isokinetic strength tests at different speeds (60, 180, 0 °/s) and magnetic resonance imaging (MRI) to analyse quadriceps femoris and hamstring muscle volume. Pearson’s correlation coefficients revealed significant correlations between both the quadriceps volume asymmetries and the maximum knee extension asymmetries (r = .60 to r = .72) as well as the hamstring volume asymmetries and the maximum knee flexion asymmetries (r = .39 to r = .52). It is assumed that bilateral differences in muscle volume in part explain the existence of strength asymmetries and that unilateral resistance training of the lower extremity could reduce strength asymmetries by increasing muscle siz

    Spatial and temporal dynamics of suspended sediment concentrations in coastal waters of the South China Sea, off Sarawak, Borneo: ocean colour remote sensing observations and analysis

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    High-quality ocean colour observations are increasingly accessible to support various monitoring and research activities for water quality measurements. In this paper, we present a newly developed regional total suspended solids (TSSs) empirical model using MODIS Aqua's Rrs(530) and Rrs(666) reflectance bands to investigate the spatial and temporal variation in TSS dynamics along the southwest coast of Sarawak, Borneo, with the application of the Open Data Cube (ODC) platform. The performance of this TSS retrieval model was evaluated using error metrics (bias = 1.0, MAE = 1.47, and RMSE = 0.22, in milligrams per litre) with a log10 transformation prior to calculation as well as using a k-fold cross-validation technique. The temporally averaged map of the TSS distribution, using daily MODIS Aqua satellite datasets from 2003 until 2019, revealed that large TSS plumes were detected – particularly in the Lupar and Rajang coastal areas – on a yearly basis. The average TSS concentration in these coastal waters was in the range of 15–20 mg L−1. Moreover, the spatial map of the TSS coefficient of variation (CV) indicated strong TSS variability (approximately 90 %) in the Samunsam–Sematan coastal areas, which could potentially impact nearby coral reef habitats in this region. Study of the temporal TSS variation provides further evidence that monsoonal patterns drive the TSS release in these tropical water systems, with distinct and widespread TSS plume variations observed between the northeast and southwest monsoon periods. A map of relative TSS distribution anomalies revealed strong spatial TSS variations in the Samunsam–Sematan coastal areas, while 2010 recorded a major increase (approximately 100 %) and widespread TSS distribution with respect to the long-term mean. Furthermore, study of the contribution of river discharge to the TSS distribution showed a weak correlation across time at both the Lupar and Rajang river mouth points. The variability in the TSS distribution across coastal river points was studied by investigating the variation in the TSS pixels at three transect points, stretching from the river mouth into territorial and open-water zones, for eight main rivers. The results showed a progressively decreasing pattern of nearly 50 % in relation to the distance from shore, with exceptions in the northeast regions of the study area. Essentially, our findings demonstrate that the TSS levels on the southwest coast of Sarawak are within local water quality standards, promoting various marine and socio-economic activities. This study presents the first observation of TSS distributions in Sarawak coastal systems with the application of remote sensing technologies and aims at enhancing coastal sediment management strategies for the sustainable use of coastal waters and their resources.</p

    Study protocol for THINK : a multinational open-label phase I study to assess the safety and clinical activity of multiple administrations of NKR-2 in patients with different metastatic tumour types

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    Introduction: NKR-2 are autologous T cells genetically modified to express a chimeric antigen receptor (CAR) comprising a fusion of the natural killer group 2D (NKG2D) receptor with the CD3 zeta signalling domain, which associates with the adaptor molecule DNAX-activating protein of 10 kDa (DAP10) to provide co-stimulatory signal upon ligand binding. NKG2D binds eight different ligands expressed on the cell surface of many tumour cells and which are normally absent on non-neoplastic cells. In preclinical studies, NKR-2 demonstrated long-term antitumour activity towards a breadth of tumour indications, with maximum efficacy observed after multiple NKR-2 administrations. Importantly, NKR-2 targeted tumour cells and tumour neovasculature and the local tumour immunosuppressive microenvironment and this mechanism of action of NKR-2 was established in the absence of preconditioning. Methods and analysis: This open-label phase I study will assess the safety and clinical activity of NKR-2 treatment administered three times, with a 2-week interval between each administration in different tumour types. The study will contain two consecutive segments: a dose escalation phase followed by an expansion phase. The dose escalation study involves two arms, one in solid tumours (five specific indications) and one in haematological tumours (two specific indications) and will include three dose levels in each arm: 3x10(8), 1x10(9) and 3x10(9) NKR-2 per injection. On the identification of the recommended dose in the first segment, based on dose-limiting toxicity occurrences, the study will expand to seven different cohorts examining the seven different tumour types separately. Clinical responses will be determined according to standard Response Evaluation Criteria In Solid Tumors (RECIST) criteria for solid tumours or international working group response criteria in haematological tumours. Ethics approval and dissemination: Ethical approval has been obtained at all sites. Written informed consent will be taken from all participants. The results of this study will be disseminated through presentation at international scientific conferences and reported in peer-reviewed scientific journals
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